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Circulating tumor cells (CTCs) are intact cancer cells shed from tumors into the bloodstream. Learn what they are, why they matter, and how they're captured.

CTCs and ctDNA are both liquid biopsy analytes, but only CTCs preserve whole, intact cells. Here's how they differ and when each is the right choice.

CTCs offer a non-invasive way to track tumor dynamics across an oncology trial — enumeration, genomics, and functional assays from serial blood draws.

Tissue biopsy and liquid biopsy answer different clinical questions. Here is when each makes sense and where intact CTCs bridge the two approaches.